Here’s what you’ll learn when you read this article: Why adding long-acting PYY to GLP-1 therapy showed only modest benefits and meaningful tolerability limits in human studies. How to interpret add-on obesity drug…
Here’s what you’ll learn when you read this article: Why targeting visceral and liver fat differs from appetite-first weight-loss drugs, and what early human data actually show. How INHBE and ALK7 gene-silencing works…
Here’s what you’ll learn when you read this article: How Wegovy tablets work, who qualifies under FDA criteria, and what the evidence shows about weight change and cardiovascular outcomes in eligible adults, using…
Here’s what you’ll learn when you read this article: ActRIIA/B inhibition shows promise in preserving lean muscle during rapid weight loss, unlike GLP-1 drugs alone. New therapies like LAE102 and dual ligand blockers…
Here’s what you’ll learn when you read this article: GLP‑1 and dual agonist drugs like tirzepatide have shown the ability to slow tumor growth in obesity‑linked cancers, especially in preclinical models. Early human…
Here’s what you’ll learn when you read this article: The FDA removed black box warnings for most systemic HRT products in late 2025, reshaping menopause care. Timing of therapy initiation now plays a…
How the 2025 Expert Consensus and MENO‑ABC Trial Challenge Old Rules Here’s what you’ll learn when you read this article: The 2025 expert consensus opens the door to case-by-case HRT use in low-risk…
Takeaways FGF21 and GDF15 analogs offer distinct mechanisms beyond GLP-1 for treating obesity and metabolic disease. Late-stage trials show promising effects on liver fat, appetite control, and thermogenesis with fewer GI side effects.…
Takeaways Brown fat activation raises calorie burn without suppressing appetite or affecting mood. Pharmacological BAT activation shows clinical promise with fewer side effects than older weight loss drugs. Combination strategies using BAT activators…
Takeaways Wearable nanobiosensors offer real-time hormone tracking through sweat or interstitial fluid. Closed-loop adaptive systems adjust HRT dosing based on live feedback instead of static lab tests. These technologies enhance precision and safety…