Advanced Weight Management

Oct 19

Muscle-Preserving Combos: The Promise of Bimagrumab + GLP‑1 in Advanced Weight Management

By Damian Williams Medical Weight Loss

Takeaways Bimagrumab plus GLP-1 therapy may preserve muscle while promoting near-total fat loss. Protecting lean mass improves long-term strength, metabolism, and quality of life. Functional outcomes, not just body composition, will shape future…

Medical Weight Loss

Muscle-Preserving Combos: The Promise of Bimagrumab + GLP‑1 in Advanced Weight Management

Medical Weight Loss

Single-Shot Incretin Gene Therapy for Obesity: RJVA-002 and the Future of Endogenous GLP-1/GIP Modulation

Takeaways RJVA-002 uses gene therapy to deliver GLP-1 and GIP directly from pancreatic beta cells in a nutrient-responsive way. Preclinical studies in obese mice show up to 30% body weight loss and improved…

Medical Weight Loss

Once-Monthly MariTide (AMG-133): New Hope in Durable Obesity Treatment

Takeaways Once-monthly MariTide led to up to 17.5% weight loss in 52 weeks, with minimal regain after stopping treatment. The drug combines GLP-1 and glucagon receptor activity, offering fat burn and appetite suppression…

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